23 September videos (review4 on vimeo, lesson5 on vimeo) - Patrick Boyle
How do you engineer a microbe to produce an interesting small molecule? What design principles can be applied to un-designed (i.e. evolved) microbes? How do we find good biological parts? How do we know if an engineered microbe is performing as expected? We will review Design, Build, and Test strategies appropriate for engineering the metabolism of bacteria and yeast.
PDFs available if requested
General review of synthetic biology tools and methods for metabolic engineering
Recent publication on the production of opiods in yeast
Publication on the use of DNA synthesis and bioinformatics to discover novel enzymes